Clinical assessment of inflammatory bowel disease activity: a critical overview

  • Adam Fabisiak Department of Biochemistry, Faculty of Medicine, Medical University of Lodz, Poland
  • Natalia Murawska Department of Biochemistry, Faculty of Medicine, Medical University of Lodz, Poland
  • Anna Mokrowiecka Department of Digestive Tract Diseases, Faculty of Medicine, Medical University of Lodz, Poland
  • Ewa Małecka-Panas Department of Digestive Tract Diseases, Faculty of Medicine, Medical University of Lodz, Poland
  • Jakub Fichna Department of Biochemistry, Faculty of Medicine, Medical University of Lodz, Poland Mossakowski Medical Research Centre, Polish Academy of Sciences, Warsaw, Poland
Keywords: disease activity index, disease classification, endoscopic and histopathological changes

Abstract

Crohn’s disease (CD) and ulcerative colitis (UC), which belong to the group of inflammatory bowel diseases (IBD), are chronic inflammatory conditions of the gastrointestinal (GI) tract. Over the last eighty years the overview of IBD has evolved, along with disease symptom recognition, hypotheses on etiology and recommendations for clinical treatment. This review focuses on the clinical aspects of IBD throughout the years and discusses the most recent and future concepts in IBD diagnosis.