Cerebrovascular mediated subclinical brain injury – interaction between cardiovascular function, brain structure and cognitive function – study rationale, design and principal methods

Authors

  • Katarzyna Katulska Department of Radiology, Poznan University of Medical Sciences, Poland
  • Andrzej Minczykowski Department of Cardiology – Intensive Therapy, Poznan University of Medical Sciences, Poland
  • Jarosław Piskorski Institute of Physics, University of Zielona Góra, Poland
  • Mateusz Wykrętowicz Department of Radiology, Poznan University of Medical Sciences, Poland
  • Marek Stajgis Department of Radiology, Poznan University of Medical Sciences, Poland
  • Przemysław Guzik Department of Cardiology – Intensive Therapy, Poznan University of Medical Sciences, Poland
  • Andrzej Wykrętowicz Department of Cardiology – Intensive Therapy, Poznan University of Medical Sciences, Poland

DOI:

https://doi.org/10.20883/medical.e65

Keywords:

brain structure, cognitive function, arterial stiffness, arterio-vascular coupling, gray matter volume, white matter lesions

Abstract

Project entitled “Cerebrovascular mediated subclinical brain injury – interaction between cardiovascular function, brain structure and cognitive function- study rationale, design and principal methods” is a cross-sectional study in a group of older individuals with no apparent symptoms of stroke, transient ischemic attacks or cognitive impairment. The primary aim of the projects is further our understanding of the patomechanism of cerebrovascular disease associate brain injury as well as vascular cognitive impairment and give a better insight into the interplay between arterial wall, ventriculo-vascular coupling, wave reflection and pulsatility of the flow and how these interplays are mirrored by MRI neuroimaging. With our novel, interdisciplinary approach, we will define the methodology and build tools for those who want to follow in this challenging and non-standard direction.

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Published

2014-06-30

How to Cite

1.
Katulska K, Minczykowski A, Piskorski J, Wykrętowicz M, Stajgis M, Guzik P, et al. Cerebrovascular mediated subclinical brain injury – interaction between cardiovascular function, brain structure and cognitive function – study rationale, design and principal methods. JMS [Internet]. 2014 Jun. 30 [cited 2024 Apr. 19];83(2):177-81. Available from: https://jms.ump.edu.pl/index.php/JMS/article/view/65

Issue

Vol. 83 No. 2 (2014)

Section

The Rationale, Design and Methods of New Studies

License

Copyright (c) 2014 Katarzyna Katulska, Andrzej Minczykowski, Jarosław Piskorski, Mateusz Wykrętowicz, Marek Stajgis, Przemysław Guzik, Andrzej Wykrętowicz

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Received 2016-02-17
Published 2014-06-30