The effects of submaximal exercise on a treadmill on the recovery of the stiffness index and reflection index in men with untreated hypertension

Kamila Miętkiewska-Szwacka; Magdalena Kujawska-Łuczak; Tomasz Piorunek; Szczepan Cofta; Karolina Hoffmann; Katarzyna Grabańska-Martyńska; Magdalena Roszak; Ewa Wysocka; Maciej Cymerys

doi:10.20883/medical.e504

Authors

Kamila Miętkiewska-Szwacka Department of Internal Medicine, Poznan University of Medical Sciences, Poland https://orcid.org/0000-0002-5977-4620
Magdalena Kujawska-Łuczak Department of Internal Medicine, Metabolic Disorders, and Hypertension, Poznan University of Medical Sciences, Poland https://orcid.org/0000-0003-2008-6633
Tomasz Piorunek Department of Pulmonology, Allergology, and Respiratory Oncology, Poznan University of Medical Sciences, Poland https://orcid.org/0000-0002-2257-4967
Szczepan Cofta Department of Pulmonology, Allergology, and Respiratory Oncology, Poznan University of Medical Sciences, Poland https://orcid.org/0000-0002-8849-5487
Karolina Hoffmann Department of Internal Medicine, Metabolic Disorders, and Hypertension, Poznan University of Medical Sciences, Poland https://orcid.org/0000-0001-6148-4094
Katarzyna Grabańska-Martyńska Department of Internal Medicine, Poznan University of Medical Sciences, Poland https://orcid.org/0000-0003-2219-1883
Magdalena Roszak Department of Computer Science and Statistics, Poznan University of Medical Sciences, Poland https://orcid.org/0000-0001-6495-6771
Ewa Wysocka Department of Laboratory Diagnostics, Poznan University of Medical Sciences, Poland https://orcid.org/0000-0002-4101-7656
Maciej Cymerys Department of Internal Medicine, Poznan University of Medical Sciences, Poland https://orcid.org/0000-0002-3284-3665

DOI:

https://doi.org/10.20883/medical.e504

Keywords:

arterial stiffness, exercise, post-exercise recovery, hypertension

Abstract

Aim. Increased arterial stiffness is a risk factor for cardiovascular disease (CVD). Adult men with untreated hypertension are at risk of future CVD. The study aimed to compare the effects of a submaximal exercise on the recovery of the two descriptors of arterial pressure waveform, i.e. stiffness index (SI) and reflection index (RI), between men with untreated hypertension (HA) and healthy peers.

Material and Methods. The study included 70 Caucasian men with untreated primary HA and 30 normotensive men. Blood pressure, SI and RI were determined by photoplethysmography before and 6 minutes after a submaximal (up to 85% of age-predicted maximal heart rate) exercise on a treadmill.

Results. Baseline SI was higher in HA than control men (6.06 [0.66] vs. 6.61 [0.84] m/s; p=0.0019) and remained significantly increased during post-exercise recovery only in HA men (7.59 [1.6] vs. 6.18 [0.85] m/s; p<0.0001). Pre-exercise RI did not differ between HA and healthy men (50.74 [14.17] vs 48.9 [14.86]%). Six minutes after the exercise, RI higher in HA patients than in healthy men (45.26[15.33] vs 36.2 [13.18]%; p=0.0058).

Conclusions. Arterial stiffness is higher in men with HA both at rest and 6 minutes after exercise. Compared with healthy men, those with HA have more increased arterial tone and impaired vasodilation but only during the recovery. It suggests that untreated HA patients have abnormal mechanical properties of arterial pressure waveforms during the post-exercise recovery.

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