Benefits of prenatal and postnatal vitamin D supplementation

Alicja Kołodziejczyk-Nowotarska; Renata Bokiniec; Joanna Seliga-Siwecka

doi:10.20883/medical.e498

Authors

Alicja Kołodziejczyk-Nowotarska Neonatal and Intensive Care Department, Medical University of Warsaw, Poland https://orcid.org/0000-0002-9380-4723
Renata Bokiniec Neonatal and Intensive Care Department, Medical University of Warsaw, Poland https://orcid.org/0000-0002-1164-8406
Joanna Seliga-Siwecka Neonatal and Intensive Care Department, Medical University of Warsaw, Poland https://orcid.org/0000-0002-4628-0541

DOI:

https://doi.org/10.20883/medical.e498

Keywords:

vitamin D deficiency, supplementation in pregnancy, infants, neonates

Abstract

The best evidence for the role of vitamin D in infants is its influence on skeletal growth, however, the pleiotropic actions of vitamin D in the foetus and neonates are under-researched. The systematic reviews, based mostly on observational studies, suggest correlations between prenatal and postnatal supplementation and the occurrence of allergy, respiratory infections, sepsis or mental and behavioural development. Some of these studies focused on subgroups of neonates, such as preterm infants, investigating the influence inter alia on sepsis, bronchopulmonary dysplasia, and necrotising enterocolitis. Currently, there is a need for randomised trials for proof of the skeletal and pleiotropic effects of vitamin D in infants.

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Benefits of prenatal and postnatal vitamin D supplementation

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