The utility of cerebral oxygenation monitoring in premature neonates




NIRS, near-infrared spectroscopy, preterm, neonate, neonatology, cerebral oxygenation


Near-infrared spectroscopy allows the measurement of cerebral oxygenation in preterm infants. This study aimed to demonstrate several highly relevant clinical situations in preterm infants in which the standard set of monitoring parameters without near-infrared spectroscopy is not sufficient to detect possible adverse situations, possibly resulting in severe complications, i.e. adverse neurological outcomes. The examples include situations of low blood pressure, persistent open ductus arteriosus, malfunctioning autoregulation of the brain oxygenation, and periods of irregular breathing. Without near-infrared spectroscopy, it is impossible to determine whether such a situation imposes any risk for the brain, whereas the measurement of cerebral oxygenation as an additional source of information enables the clinician to recognise these conditions and modify treatment or use countermeasures to protect the patient from brain damage and ensuing lifelong disabilities.


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van Bel F, Lemmers P, Naulaers G. Monitoring Neonatal Regional Cerebral Oxygen Saturation in Clinical Practice: Value and Pitfalls. Neonatology. 2008;94(4):237-244.

Wolf M, Naulaers G, van Bel F, Kleiser S, Greisen G. A Review of near Infrared Spectroscopy for Term and Preterm Newborns. Journal of Near Infrared Spectroscopy. 2012 Jan;20(1):43-55.

Fanaroff JM, Fanaroff AA. Blood pressure disorders in the neonate: Hypotension and hypertension. Seminars in Fetal and Neonatal Medicine. 2006 Jun;11(3):174-181.

Hyttel-Sorensen S, Austin T, van Bel F, Benders M, Claris O, Dempsey E, Fumagalli M, Greisen G, Grevstad B, Hagmann C, Hellström-Westas L, Lemmers P, Lindschou J, Naulaers G, van Oeveren W, Pellicer A, Pichler G, Roll C, Skoog M, Winkel P, Wolf M, Gluud C. A phase II randomized clinical trial on cerebral near-infrared spectroscopy plus a treatment guideline versus treatment as usual for extremely preterm infants during the first three days of life (SafeBoosC): study protocol for a randomized controlled trial. Trials. 2013;14(1):120.




How to Cite

Nesargi S, Nitsch A, Wolf M. The utility of cerebral oxygenation monitoring in premature neonates. JMS [Internet]. 2020 Dec. 30 [cited 2024 Jun. 21];89(4):e485. Available from:



Review Papers
Received 2020-11-12
Accepted 2020-12-06
Published 2020-12-30