vitamin K, dietary supplements, body weight, leptin, adiponectin
Background: The aim of this systematic review was to assess the effect of vitamin K supplementation on anthropometric parameters and adipokine levels in adults.
Methods: Four databases (PubMed, Web of Sciences, Scopus and the Cochrane Library) were searched to select studies in which the effect of vitamin K supplementation on body weight, body mass index (BMI), fat mass, leptin and adiponectin levels were assessed.
Results: We identified nine studies that included a total of 542 subjects. Vitamin K supplementation did not influence body weight, BMI and percentage of fat mass. In addition, the effect of vitamin K supplementation on adipokines levels was equivocal.
Conclusions: Vitamin K supplementation did not affect anthropometric parameters and adipokines levels. Nevertheless, further studies are needed to clarify the effect of vitamin K supplementation on these parameters in adults.