HPV-related HNC – new challenge and hope for head and neck cancer subjects

  • Krzysztof Szyfter 1. Institute of Human Genetics Polish Academy of Sciences, Poznan, Poland
  • Katarzyna Kiwerska 1. Institute of Human Genetics Polish Academy of Sciences, Poznan, Poland
  • Małgorzata Wierzbicka 1. Institute of Human Genetics Polish Academy of Sciences, Poznan, Poland 2. Dept. of Otolaryngology, Head and Neck Surgery, Poznań Uniwersity of Medical Sciences, Poznań, Poland
Keywords: HPV-related cancer, head and neck, epidemiology, treatment

Abstract

In recent years there are observed substantial changes in epidemiology of head and neck cancer. An incidence of laryngeal cancer is declining as a consequence of decreased tobacco smoking. Contrary, oropharyngeal cancer associated with HPV infection transmitted on sexual way is becoming much more frequent. The latter one is characterized with a better prognosis that most likely does not require intensive therapy. De-escalation of therapy in case of HPV-associated tumor is a matter of current studies.