The importance of epigenome research in the diagnosis and treatment of endometriosis

  • Przemysław Krzysztof Wirstlein Department of Obstetrics, Gynecology and Gynecological Oncology, Division of Reproduction. Poznan University of Medical Sciences
  • Paweł P. Jagodziński Department of Biochemistry and Molecular Biology, Poznan University of Medical Sciences, Poland
  • Małgorzata Szczepańska Department of Biochemistry and Molecular Biology, Poznan University of Medical Sciences, Poland
Keywords: endometriosis, gene expression, methylation

Abstract

The causes of endometriosis remain unexplained. Studying the molecular mechanisms at the origin of the lesions leads to conclusions about the important role of the epigenome. This mini-review is a summary of the current state of knowledge about the processes of epigenetic control of gene expression involved in the pathogenesis of endometriosis.