Factors associated with overhydration in peritoneal dialysis patients

Authors

  • Dorota Sikorska Department of Rheumatology and Rehabilitation; University of Medical Sciences, Poznan, Poland
  • Krzysztof Pawlaczyk Department of Nephrology, Transplantology and Internal Diseases; University of Medical Sciences, Poznan, Poland Divisions of Renal Medicine and Baxter Novum, Department of Clinical Science, Intervention, and Technology, Karolinska Institutet, Stockholm, Sweden
  • Anna Olewicz-Gawlik Department of Infectious Diseases; University of Medical Sciences, Poznan, Poland
  • Magdalena Roszak Department of Computer Science and Statistics; University of Medical Sciences, Poznan, Poland
  • Włodzimierz Samborski Department of Rheumatology and Rehabilitation; University of Medical Sciences, Poznan, Poland
  • Ewa Baum Department of Nephrology, Transplantology and Internal Diseases; University of Medical Sciences, Poznan, Poland
  • Małgorzata Kałużna Department of Endocrinology, Metabolism and Internal Medicine; University of Medical Sciences, Poznan, Poland
  • Maria Wanic-Kossowska Department of Nephrology, Transplantology and Internal Diseases; University of Medical Sciences, Poznan, Poland
  • Bengt Lindholm Divisions of Renal Medicine and Baxter Novum, Department of Clinical Science, Intervention, and Technology, Karolinska Institutet, Stockholm, Sweden
  • Andrzej Oko Department of Nephrology, Transplantology and Internal Diseases; University of Medical Sciences, Poznan, Poland

DOI:

https://doi.org/10.20883/jms.2017.193

Keywords:

peritoneal dialysis, bioelectrical impedance analysis, state of hydration

Abstract

Aim. Overhydration is a prevalent problem in peritoneal dialysis (PD) patients. The aim of the study was to evaluate the effect of several factors on the development of overhydration in PD patients.
Material and Methods. The study was performed on 74 PD patients, who were divided into two groups according to bioimpedance analysis hydration status (OHBIA): Group A OHBIA < 1.1 L (n = 40) and Group B OHBIA ? 1.1 L (n = 34). The assessments of the adequacy of the dialysis dosage were based on the Kt/V ratio as well as weekly creatinine clearance. To evaluate the permeability of the peritoneal membrane a standard peritoneal equilibration test was used.
Results. A statistically significant difference between the groups was found in: the average age of patients (53 ± 18 vs. 62 ± 14 years; p < 0.03), the prevalence of diabetes (27.5% vs. 55.9%; p < 0.02) and residual diuresis (1.7 ± 0.8 vs 1.2 ± 0.9 L; p < 0.05). There was no statistically significant difference in gender distribution, although attention is paid to the greater participation of male in overhydrated group. The study found no statistically significant differences between PD vintage, type of PD, assessment of adequacy of PD and other parameters describing the PD method. Logistic regression model selected diabetes (p < 0.03) as a significant risk factor for the occurrence of hypervolemia.
Conclusions. Diabetes and older age are potential predisposing factors for the development of overhydration in PD patients. Overhydrated PD patients may have relatively high parameters regarding adequacy of dialysis therapy. Probably the most important protective factor in PD patients is residual diuresis

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Published

2017-03-30

Issue

Vol. 86 No. 1 (2017)

Section

Original Papers

License

Copyright (c) 2017 Dorota Sikorska, Krzysztof Pawlaczyk, Anna Olewicz-Gawlik, Magdalena Roszak, Włodzimierz Samborski, Ewa Baum, Małgorzata Kałużna, Maria Wanic-Kossowska, Bengt Lindholm, Andrzej Oko

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This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

How to Cite

1.
Sikorska D, Pawlaczyk K, Olewicz-Gawlik A, Roszak M, Samborski W, Baum E, et al. Factors associated with overhydration in peritoneal dialysis patients. JMS [Internet]. 2017 Mar. 30 [cited 2024 Nov. 22];86(1):7-12. Available from: https://jms.ump.edu.pl/index.php/JMS/article/view/193