Factors associated with overhydration in peritoneal dialysis patients

Authors

  • Dorota Sikorska Department of Rheumatology and Rehabilitation; University of Medical Sciences, Poznan, Poland
  • Krzysztof Pawlaczyk Department of Nephrology, Transplantology and Internal Diseases; University of Medical Sciences, Poznan, Poland Divisions of Renal Medicine and Baxter Novum, Department of Clinical Science, Intervention, and Technology, Karolinska Institutet, Stockholm, Sweden
  • Anna Olewicz-Gawlik Department of Infectious Diseases; University of Medical Sciences, Poznan, Poland
  • Magdalena Roszak Department of Computer Science and Statistics; University of Medical Sciences, Poznan, Poland
  • Włodzimierz Samborski Department of Rheumatology and Rehabilitation; University of Medical Sciences, Poznan, Poland
  • Ewa Baum Department of Nephrology, Transplantology and Internal Diseases; University of Medical Sciences, Poznan, Poland
  • Małgorzata Kałużna Department of Endocrinology, Metabolism and Internal Medicine; University of Medical Sciences, Poznan, Poland
  • Maria Wanic-Kossowska Department of Nephrology, Transplantology and Internal Diseases; University of Medical Sciences, Poznan, Poland
  • Bengt Lindholm Divisions of Renal Medicine and Baxter Novum, Department of Clinical Science, Intervention, and Technology, Karolinska Institutet, Stockholm, Sweden
  • Andrzej Oko Department of Nephrology, Transplantology and Internal Diseases; University of Medical Sciences, Poznan, Poland

DOI:

https://doi.org/10.20883/jms.2017.193

Keywords:

peritoneal dialysis, bioelectrical impedance analysis, state of hydration

Abstract

Aim. Overhydration is a prevalent problem in peritoneal dialysis (PD) patients. The aim of the study was to evaluate the effect of several factors on the development of overhydration in PD patients.
Material and Methods. The study was performed on 74 PD patients, who were divided into two groups according to bioimpedance analysis hydration status (OHBIA): Group A OHBIA < 1.1 L (n = 40) and Group B OHBIA ? 1.1 L (n = 34). The assessments of the adequacy of the dialysis dosage were based on the Kt/V ratio as well as weekly creatinine clearance. To evaluate the permeability of the peritoneal membrane a standard peritoneal equilibration test was used.
Results. A statistically significant difference between the groups was found in: the average age of patients (53 ± 18 vs. 62 ± 14 years; p < 0.03), the prevalence of diabetes (27.5% vs. 55.9%; p < 0.02) and residual diuresis (1.7 ± 0.8 vs 1.2 ± 0.9 L; p < 0.05). There was no statistically significant difference in gender distribution, although attention is paid to the greater participation of male in overhydrated group. The study found no statistically significant differences between PD vintage, type of PD, assessment of adequacy of PD and other parameters describing the PD method. Logistic regression model selected diabetes (p < 0.03) as a significant risk factor for the occurrence of hypervolemia.
Conclusions. Diabetes and older age are potential predisposing factors for the development of overhydration in PD patients. Overhydrated PD patients may have relatively high parameters regarding adequacy of dialysis therapy. Probably the most important protective factor in PD patients is residual diuresis

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References

Van Biesen W, Williams JD, Covic AC, et al. Fluid status in peritoneal dialysis patients: the European Body Composition Monitoring (EuroBCM) study cohort. PLoS One. 2011;6(2):e17148.

Devolder I, Verleysen A, Vijt D, Vanholder R, Van Biesen W. Body composition, hydration, and related parameters in hemodialysis versus peritoneal dialysis patients. Perit Dial Int. 2010;30(2):208-214.

van Biesen W, Claes K, Covic A, et al. A multicentric, international matched pair analysis of body composition in peritoneal dialysis versus haemodialysis patients. Nephrol Dial Transplant. 2013;28(10):2620-2628.

Nakayama M, Kasai K, Imai H, Group TRMS. Novel low Na peritoneal dialysis solutions designed to optimize Na gap of effluent: kinetics of Na and water removal. Perit Dial Int. 2009;29(5):528-535.

Konings CJ, Kooman JP, Schonck M, et al. Fluid status in CAPD patients is related to peritoneal transport and residual renal function: evidence from a longitudinal study. Nephrol Dial Transplant. 2003;18(4):797-803.

Davies SJ, Brown B, Bryan J, Russell GI. Clinical evaluation of the peritoneal equilibration test: a population-based study. Nephrol Dial Transplant. 1993;8(1):64-70.

Wabel P, Chamney P, Moissl U, Jirka T. Importance of whole-body bioimpedance spectroscopy for the management of fluid balance. Blood Purif. 2009;27(1):75-80.

Twardowski ZJ, Nolph KD, Khanna R, et al. Peritoneal equilibration test. Perit.Dial.Int.1987. p. 138-148.

Bargman JM, Thorpe KE, Churchill DN, Group CPDS. Relative contribution of residual renal function and peritoneal clearance to adequacy of dialysis: a reanalysis of the CANUSA study. J Am Soc Nephrol. 2001;12(10):2158-2162.

Szeto CC, Wong TY, Leung CB, et al. Importance of dialysis adequacy in mortality and morbidity of chinese CAPD patients. Kidney Int. 2000;58(1):400-407.

Juan-Garcia I, Puchades MJ, Sanjuan R, et al. Echocardiographic impact of hydration status in dialysis patients. Nefrologia. 2012;32(1):94-102.

Kwan BC, Szeto CC, Chow KM, et al. Bioimpedance Spectroscopy for the Detection of Fluid Overload in Chinese Peritoneal Dialysis Patients. Perit Dial Int. 2014.

Sipahi S, Hur E, Demirtas S, et al. Body composition monitor measurement technique for the detection of volume status in peritoneal dialysis patients: the effect of abdominal fullness. Int Urol Nephrol. 2011;43(4):1195-1199.

Tang W, Xue T, Lu XH, Luo YJ, Wang T. Factors contributing to formation of edema in volume overloaded continuous ambulatory peritoneal dialysis patients. Perit Dial Int. 2011;31(2):160-167.

Demirci MS, Demirci C, Ozdogan O, et al. Relations between malnutrition-inflammation-atherosclerosis and volume status. The usefulness of bioimpedance analysis in peritoneal dialysis patients. Nephrol Dial Transplant. 2011;26(5):1708-1716.

Guo Q, Yi C, Li J, Wu X, Yang X, Yu X. Prevalence and risk factors of fluid overload in Southern Chinese continuous ambulatory peritoneal dialysis patients. PLoS One. 2013;8(1):e53294.

Hung SC, Kuo KL, Peng CH, et al. Volume overload correlates with cardiovascular risk factors in patients with chronic kidney disease. Kidney Int. 2013.

Hung SC, Kuo KL, Peng CH, et al. Volume overload correlates with cardiovascular risk factors in patients with chronic kidney disease. Kidney Int. 2014;85(3):703-709.

Garagarza C, Joao-Matias P, Sousa-Guerreiro C, et al. Nutritional status and overhydration: can bioimpedance spectroscopy be useful in haemodialysis patients? Nefrologia. 2013;33(5):667-674.

Marron B, Remon C, Perez-Fontan M, Quiros P, Ortiz A. Benefits of preserving residual renal function in peritoneal dialysis. Kidney Int Suppl. 2008(108):S42-51.

Matsuda A, Matsumura O, Ogawa T, et al. Contribution of residual renal function on peritoneal solute transport in dialysis patients. Am J Nephrol. 2010;32(3):187-193.

Cnossen TT, Konings CJ, Fagel WJ, et al. Fluid state and blood pressure control: no differences between APD and CAPD. ASAIO J. 2012;58(2):132-136.

Davenport A, Willicombe M. Comparison of fluid status in patients treated by different modalities of peritoneal dialysis using multi-frequency bioimpedance. Int J Artif Organs. 2009;32(11):779-786.

Asghar RB, Green S, Engel B, Davies SJ. Relationship of demographic, dietary, and clinical factors to the hydration status of patients on peritoneal dialysis. Perit Dial Int. 2004;24(3):231-239.

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Published

2017-03-30

How to Cite

1.
Sikorska D, Pawlaczyk K, Olewicz-Gawlik A, Roszak M, Samborski W, Baum E, et al. Factors associated with overhydration in peritoneal dialysis patients. JMS [Internet]. 2017 Mar. 30 [cited 2024 Apr. 19];86(1):7-12. Available from: https://jms.ump.edu.pl/index.php/JMS/article/view/193

Issue

Vol. 86 No. 1 (2017)

Section

Original Papers

License

Copyright (c) 2017 Dorota Sikorska, Krzysztof Pawlaczyk, Anna Olewicz-Gawlik, Magdalena Roszak, Włodzimierz Samborski, Ewa Baum, Małgorzata Kałużna, Maria Wanic-Kossowska, Bengt Lindholm, Andrzej Oko

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Received 2017-01-08
Published 2017-03-30