Characteristics of Regulatory T cells


  • Magdalena Frydrychowicz Chair and Department of Clinical Immunology, Poznan University of Medical Sciences, Poland
  • Maciej Boruczkowski Chair and Department of Clinical Immunology, Poznan University of Medical Sciences, Poland
  • Agata Kolecka-Bednarczyk Chair and Department of Clinical Immunology, Poznan University of Medical Sciences, Poland
  • Renata Jenek Chair and Department of Clinical Immunology, Poznan University of Medical Sciences, Poland
  • Joanna Rosołowska Chair and Department of Clinical Immunology, Poznan University of Medical Sciences, Poland
  • Agnieszka Pluto-Prądzyńska Chair and Department of Clinical Immunology, Poznan University of Medical Sciences, Poland
  • Grzegorz Dworacki Chair and Department of Clinical Immunology, Poznan University of Medical Sciences, Poland



Tregs, regulatory T cells, autoimmunity, cancer


Regulatory T cells (Tregs) is heterogenic subpopulation of T cells that is able to suppress function of effector cells during the immune response. Among them are natural (nTreg) and induced Treg (Tr1, Th3, CD4+CD25-). CD25, CD45Ro, CD152, GITR, LAG-3, several adhesion molecules, chemokine receptors as well as Toll-like receptors are present on the surface of Treg. Mechanism of suppression used by nTreg is not completely understood.


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How to Cite

Frydrychowicz M, Boruczkowski M, Kolecka-Bednarczyk A, Jenek R, Rosołowska J, Pluto-Prądzyńska A, Dworacki G. Characteristics of Regulatory T cells. JMS [Internet]. 2016 Dec. 29 [cited 2023 Jun. 6];85(4):323-6. Available from:



Review Papers
Received 2016-12-12
Published 2016-12-29