AbstractIntroduction. Sympathetic skin response (SSR) is applied in evaluation of dysfunctions in autonomic nervous system. Among others, electrical and sound stimuli are most frequently used to evoke SSR.
Aim. The aim of this study was to determine if the bell ring stimulus with parameters different from standard sound stimulation evokes similar reactions in autonomic system as electrical stimulus with defined parameters.
Material and methods. SSR parameters were recorded following simultaneous sound and electrical stimulation. Twenty young volunteers (aged 23 ± 2.1 years) were examined once with SSR and R-R interval variation (RRIV) tests in order to confirm lack of functional changes in autonomic nervous system.
Results. Values of mean amplitudes of SSR were always higher during recordings from upper limbs than the lower ones irrespective of the three types of applied stimuli. Mean values of latencies were comparable when SSR were induced with acoustic, electrical and both stimuli during recordings performed from upper and lower extremities. Bell ring stimulus influenced only mean values of SSR area recorded both from upper (p ? 0.011) and lower (p ? 0.023) extremities. Heart beats variability in RRIV recordings changed at 13.5% which is comparable to results obtained by other authors.
Conclusions. Results indicate that the application of different modalities stimuli evokes SSR with comparable parameters. Each of them can be used for objective evaluation of the sympathetic nervous system function. Both SSR and RRIV tests evaluating the function of two effector types should be applied for the diagnosis of the probable dysautonomia in patients who show unclear clinical symptoms.
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- Ravits JM. AAEM minimonograph #48. autonomic nervous system testing. Muscle and Nerve. 1997;20:919–937.
- Zygmunt A, Stanczyk J. Methods of evaluation of autonomic nervous system function. Arch Med Sci. 2010;6:11–18.
- Baba M, Watahiki Y, Matsunga M, Takebe K. Sympathetic skin response in healthy man. Electromyogr Clin Neurophysiol. 1988;28;277–283.
- Baron R, Ewing DJ. Heart rate variability. The International Federation of Clinical Neurophysiology. Electroencephalogr Clin Neurophysiol Suppl. 1999;52:283–286.
- Shahani BT, Halperin JJ, Boulu P, Cohen J. Sympathetic skin response a method of assessing unmyelinated axon dysfunction in peripheral neuropathies. J Neurol Neurosurg Psychiatry. 1984;47:536–542.
- Claus D, Schondorf R. Sympathetic skin response. In Recommendations for the practice of clinical neurophysiology. guidelines of the International Federation of Clinical Neurophysiology. 2nd ed. Edited by Deuschl G, Eisen A. Amsterdam. Elsevier Science BV 1999.
- Mathias CJ. Autonomic diseases. clinical features and laboratory evaluation. J Neurol Neurosurg Psychiatry. 2003;74:(Suppl 3);iii31–iii41.
- Vetrugno R, Liguori R, Cortelli P, Montagna P. Sympathetic skin response. basic mechanisms and clinical applications. Clin Auton Res. 2003;1:256–270.
- Elie, B, Guiheneuc, P. Sympathetic skin response. normal results in different experimental conditions. Electroencephalogr Clin Neurophysiol. 1990;76;258–267.
- Satchell PM, Seers CP. Evoked skin sympathetic nerve responses in man. J Neurol Neurosurg Psychiatry. 1987;50:1015–1021.
- Lee JH, DeLisa JA. Sympathetic Skin Response. In Manual of nerve conduction study and surface anatomy for needle electromyography. 4th ed. Philadelphia. Lippincot Williams&Wilkins, 2005.
- Yoshimura T, Yonezawa Y, Maki H, Ogawa H, Ninomiya I, Morton Caldwell W. An ECG electrode-mounted heart rate, respiratory rhythm, posture and behavior recording system. Med Biol Soc. 2004;4:2373–2374.
- Shahani BT, Day TJ, Cros D, Khalil N, Kneebone ChS. RR Interval Variation and the Sympathetic Skin Response in the Assessment of Autonomic Function in Peripheral Neurophaty. Arch Neurol. 1990;47:659–664.
- Zakrzewska-Pniewska B, Przybyłowski T, Byśkiniewicz K, Kostera-Pruszczyk A, Droszcz W, Emeryk-Szajewska B. Sympathetic skin response in obstructive sleep apnea syndrome. Acta Neurobiol Exp. 1998;58:113–121.
- Cariga P, Catley M, Mathias CJ, Savic G, Frankel HL, Ellaway PH. Organisation of the sympathetic skin response in spinal cord injury. J Neurol Neurosurg Psychiatry. 2002;72:356–360.
- Ozgocmen S, Yoldas T, Yigiter R, Kaya A, Ardicoglu O. R-R interval variation and sympathetic skin response in fibromyalgia. Arch Med Res. 2006;37:630–634.
- Levy DM, Reid G, Rowley DA, Abraham RR. Quantitative measures of sympathetic skin response in diabetes. relation to sudomotor and neurological function. J Neurol Neurosurg Psychiatry. 1992;55:902–908.
- Kucera P, Goldenberg Z, Kurca E. Sympathetic skin response. review of the method and its clinical use. Bratisl Lek Listy. 2004;105:108–116.
- Zakrzewska-Pniewska B, Jędras M. Is puritus in chronic uremic patients related to pheripheral somatic and autonomic neurophaty? Study by R-R interval variation test (RRIV) and by sympathetic skin response (SSR). Neurophysiol Clin. 2001;31:181–193.
- Chroni E, Argyriou AA, Polychronopoulos P, Sirrou V. The effect of stimulation technique on sympathetic skin responses in healthy subjects. Clin Auton Res. 2006;16:396–400.
- Łabuz-Roszak B, Pierzchała K. Assessment of autonomic nervous system in patients with epilepsy in the interictal state. A pilot study. Neurol Neurochir Pol. 2009;43:330–336.
- Deniz O, Aygül R, Kotan D, Ozdemir G, Odabaş FO, Kaya MD, Ulvi H. The effect of local corticosteroid injection on F-wave conduction velocity and sympathetic skin response in carpal tunnel syndrome. Rheumatol Int. 2012;32:1285–1290.
- Kim CT, Chun SI. Sympathetic skin response recorded by 4 channel recording system. Yonsei Med J. 1994;35:149–154.
- Choi BO, Bang OY, Sohn YH, Sunwoo IN. Sympathetic skin response and cardiovascular autonomic function tests in Parkinson's disease. Yonsei Med J. 1998;39:439–445.
- Drory VE, Korczyn AD. Symphatetic skin response. Age effect. Neurology. 1993;43:1818–1820.
- Zakrzewska-Pniewska B, Jamrozik Z. Are electrophysiological autonomic tests useful in the assessment of dysautonomia in Parkinson's disease? Parkinsonism Relat Disord. 2003;9:179–183.