A 10 year data analysis of lymphatic system metastasis and recurrence in individuals affected by malignant tumors within the oral cavity and maxillofacial region

Authors

  • Adam Dreksler Student Scientific Circle in Department of Maxillofacial Surgery, Poznan University of Medical Sciences, Poland
  • Marcin Lenkowski Student Scientific Circle in Department of Maxillofacial Surgery, Poznan University of Medical Sciences, Poland
  • Michał Marcinkowski Department of Maxillofacial Surgery, Poznan University of Medical Sciences, Poland
  • Marian Tomasz Nowaczyk Department of Maxillofacial Surgery, Poznan University of Medical Sciences, Poland
  • Krzysztof Osmola Department of Maxillofacial Surgery, Poznan University of Medical Sciences, Poland
  • Tomasz Pełczyński Student Scientific Circle in Department of Maxillofacial Surgery, Poznan University of Medical Sciences, Poland
  • Gleb Radzewicz Student Scientific Circle in Department of Maxillofacial Surgery, Poznan University of Medical Sciences, Poland
  • Samir Rahma Student Scientific Circle in Department of Maxillofacial Surgery, Poznan University of Medical Sciences, Poland

DOI:

https://doi.org/10.20883/medical.e10

Keywords:

tumors of head, tumors of neck, recurrence

Abstract

Introduction. Tumors are only second to cardiovascular diseases as a cause of death. According to World Health Organization (WHO), these statistics will increase especially within aging and well-developed countries.
Aim. The aim of the research was to analyze the frequency of recurrences and lymph node involvement in individuals affected by malignant tumor of head and neck region. Special attention was paid to tumor location, sex, age of the affected individuals as well as histological appearance of the tumor.
Material and methods. The research team has analyzed medical data record base from 2002–2011 and selected a group of 1697 individuals treated for malignant tumors within the oral cavity and maxillofacial region.
Results. Reoperation was carried out on 192 patients due to recurrences and lymph node involvement; (11.3%) of the study group. Patients were further subdivided into groups according to sex, age, histological appearance and anatomical location of tumor recurrence. Results were compared with the available literature.
Conclusions. Our data confirms the findings of other research groups in terms of accuracy of early diagnostic screening and its effect on final tumor treatment. It is also essential to accentuate the importance of post-treatment monitoring within first five years after initiation of treatment, which allows for an early determination of local recurrences and/or lymph node involvement.

Downloads

Download data is not yet available.

References

Petrisor D, Fernandes R. Reoperative maxillofacial oncology, Oral Maxillofac Surg Clin North Am. 2011 Feb;23(1):161–168.

Nowotwory złośliwe w Wielkopolsce w 2009 roku. Biuletyn nr 8 Wydawnictwo Wielkopolskiego Centrum Onkologii w Poznaniu 2011; 9–19.

Flieger S, Lewandowski L, Osmola K, Nowaczyk MT. Leczenie chorych onkologicznych w klinice chirurgii Szczękowo-Twarzowej w Poznaniu w okresie 30 lat. Poznańska Stomatologia. 1994:13–17.

Lara PC, Bordón E, Rey A, Moreno M, Lloret M, Henríquez-Hernánde LA. IGF-1R expression predicts clinical outcome in patients with locally advanced oral squamous cell carcinoma. Oral Oncol. 2011 Jul;47(7):615–619.

Agra IM, Carvalho AL, Pinto CA, Martins EP, Filho JG, Soares FA et all. Biological markers and prognosis in recurrent oral cancer after salvage surgery. Arch Otolaryngol Head Neck Surg. 2008 Jul;134(7):743–749.

Kokemuller H, Brachvogel P, Eckardt A, Hausamen JE. Effectiveness of neck dissection in metastasizing mouth carcinoma. Uni- and multivariate analysis of factors of influence. Mund Kiefer Gesichtschir. 2002 Mar;6(2): 91–97.

Rowe DE, Carroll RJ, Day CL Jr. Prognostic factors for local recurrence, metastasis, and survival rates in squamous cell carcinoma of the skin, ear, and lip. Implications for treatment modality selection. J Am Acad Dermatol. 1992 Jun;26(6):976–990.

Wolfensberger M, Albrecht S, Muller W, Zbaren P, Dulguerov P, Arnoux A et all. Follow-up after histologically verified radical resection of early cancers of the mouth cavity: results of a prospective multicenter study. Schweiz Med Wochenschr Suppl. 2000;116:12S–14S.

Agra IM, Filho JG, Martins EP, Kowalski LP. Second salvage surgery for re-recurrent oral cavity and oropharynx carcinoma. Head Neck. 2010 Aug;32(8):997–1002.

Wong LY, Wei WI, Lam LK, Yuen AP. Salvage of recurrent head and neck squamous cell carcinoma after primary curative surgery. Head Neck. 2003 Nov;25(11):953–959.

Szybiak B, Trzeciak P, Golusiński W. Role of extended histological examination in the assessment of local recurrence of tongue and floor of the mouth cancer. Rep Pract Oncol Radiother. 2012 Nov;17(6):319–323.

Boysen M, Lövdal O, Tausjö J, Winther F. The value of follow-up in patients treated for squamous cell carcinoma of the head and neck. Eur J Cancer. 1992;28(2–3): 426–430.

de Visscher AV, Manni JJ. Routine long-term follow-up in patients treated with curative intent for squamous cell carcinoma of the larynx, pharynx, and oral cavity. Does it make sense? Arch Otolaryngol Head Neck Surg. 1994 Sep;120(9):934–939.

Haas I, Hauser U, Ganzer U. The dilemma of follow-up in head and neck cancer patients. Eur Arch Otorhinolaryngol. 2001 May;258(4):177–183.

Zafereo ME, Hanasono MM, Rosenthal DI, Sturgis EM, Lewin JS, Roberts DB et al. The role of salvage surgery in patients with recurrent squamous cell carcinoma of the oropharynx. Cancer. 2009 Dec;115(24):5723–5733.

Arnold DJ, Goodwin WJ, Weed DT, Civantos FJ. Treatment of recurrent and advanced stage squamous cell carcinoma of the head and neck. Semin Radiat Oncol. 2004 Apr;14(2):190–195.

Tsang RK, Chung JC, To VS, Chan JY, Ho WK, Wei WI. Efficacy of salvage neck dissection for isolated nodal recurrences in early carcinoma of oral tongue with watchful waiting management of initial N0 neck. Head Neck. 2011 Oct;33(10):1482–1485.

Schiefke F, Hildebrandt G, Pohlmann S, Heinicke F, Hemprich A, Frerich B. Combination of surgical resection and HDR brachytherapy in patients with recurrent or advanced head nad neck carcinomas. J Craniomaxillofac Surg. 2008 Jul;36(5):285–292.

Downloads

Published

2015-09-30

Issue

Section

Original Papers

How to Cite

1.
Dreksler A, Lenkowski M, Marcinkowski M, Nowaczyk MT, Osmola K, Pełczyński T, et al. A 10 year data analysis of lymphatic system metastasis and recurrence in individuals affected by malignant tumors within the oral cavity and maxillofacial region. JMS [Internet]. 2015 Sep. 30 [cited 2024 Nov. 22];84(3):141-5. Available from: https://jms.ump.edu.pl/index.php/JMS/article/view/10