TY - JOUR AU - Jamka, Małgorzata AU - Makarewicz, Aleksandra AU - Wasiewicz-Gajdzis, Maria AU - Brylak, Jan AU - Wielińska-Wiśniewska, Hanna AU - Pawlak, Zuzanna AU - Nowak, Jan Krzysztof AU - Herzig, Karl-Heinz AU - Mądry, Edyta AU - Walkowiak, Jarosław PY - 2021/09/01 Y2 - 2024/03/29 TI - App-assured essential physical activity for the prevention of cognitive decline: changing paradigms in public health – a study protocol for a randomised controlled trial: A study protocol of the PA PROTECT study JF - Journal of Medical Science JA - JMS VL - 90 IS - 4 SE - The Rationale, Design and Methods of New Studies DO - 10.20883/medical.e530 UR - https://jms.ump.edu.pl/index.php/JMS/article/view/530 SP - e530 AB - <p>This study aims to assess the effect of an increase in daily physical activity to prevent cognitive decline, sustain brain volumes and maintain healthy biomarker levels in mild cognitive impairment (MCI) subjects aged 50-70 years. In total, 198 subjects with MCI (assessed using the Montreal Cognitive Assessment test) will be recruited and randomised into two groups: active and passive. The active group will be instructed, encouraged and motivated to increase their physical activity to at least a moderate level (≥ 10,000 steps/day), whereas the passive group should maintain their normal activity levels. All subjects will undergo cognitive assessment, neuroimaging and biomarker tests prior to and after a one-year intervention. During the intervention, physical activity will be measured by the Fitbit Inspire HR wristband. The study was registered in the German Clinical Trials Register database (registration no. DRKS00020943, date of registration: 09.03.2020, protocol version: 1.0).</p> ER -