@article{Klimaszyk_Wender-Ożegowska_Kędzia_2021, title={Maternal and foetal outcome of pregnancy in women with connective tissue diseases}, volume={90}, url={https://jms.ump.edu.pl/index.php/JMS/article/view/525}, DOI={10.20883/medical.e525}, abstractNote={<p><strong>Introduction. </strong>The majority of patients diagnosed with systemic connective tissue diseases are women of childbearing age.</p> <p><strong>Aim.</strong> The analysis of obstetric results and exacerbation rates in the pregnancies involving systemic connective tissue diseases.</p> <p><strong>Material and Methods</strong>. We retrospectively reviewed perinatal outcomes of fourteen women with systemic connective tissue diseases hospitalised in the Department of Reproduction in the period between September 2019 and July 2021.</p> <p><strong>Results. </strong>Median duration of a pregnancy was 37 weeks. One pregnancy ended in a stillbirth in week 28. Of the 13 live births, preterm delivery occurred in 5 cases. Of the 13 live-birth neonates, preterm delivery occurred in five cases. The Caesarean section rate was 57.1% and vaginal delivery rate was 42.9%. The mean birth weight of the live neonates was 2787g (SD 892), and the median Apgar score in the 1<sup>st</sup> and the 3<sup>rd</sup> minute was 10.</p> <p>In total, all 4 patients with the active disease at the time of conception and 1 who did not decide to undergo the recommended mitral valve surgery prior to pregnancy experienced symptoms indicating a disease flare-up in the course of pregnancy. None of the patients who planned their pregnancy experienced an exacerbation of the disease.</p> <p><strong>Conclusions.</strong> All patients diagnosed with systemic connective tissue diseases should receive multidisciplinary care prior to conception, during pregnancy and in the postpartum period. Furthermore, they should be monitored by a team of specialists, due to the risk of a disease exacerbation and high rates of maternal and foetal complications resulting from the underlying condition.</p>}, number={3}, journal={Journal of Medical Science}, author={Klimaszyk, Katarzyna and Wender-Ożegowska, Ewa and Kędzia, Małgorzata}, year={2021}, month={Sep.}, pages={e525} }