Characteristics of Regulatory T cells

Authors

  • Magdalena Frydrychowicz Chair and Department of Clinical Immunology, Poznan University of Medical Sciences, Poland
  • Maciej Boruczkowski Chair and Department of Clinical Immunology, Poznan University of Medical Sciences, Poland
  • Agata Kolecka-Bednarczyk Chair and Department of Clinical Immunology, Poznan University of Medical Sciences, Poland
  • Renata Jenek Chair and Department of Clinical Immunology, Poznan University of Medical Sciences, Poland
  • Joanna Rosołowska Chair and Department of Clinical Immunology, Poznan University of Medical Sciences, Poland
  • Agnieszka Pluto-Prądzyńska Chair and Department of Clinical Immunology, Poznan University of Medical Sciences, Poland
  • Grzegorz Dworacki Chair and Department of Clinical Immunology, Poznan University of Medical Sciences, Poland

DOI:

https://doi.org/10.20883/jms.2016.175

Keywords:

Tregs, regulatory T cells, autoimmunity, cancer

Abstract

Regulatory T cells (Tregs) is heterogenic subpopulation of T cells that is able to suppress function of effector cells during the immune response. Among them are natural (nTreg) and induced Treg (Tr1, Th3, CD4+CD25-). CD25, CD45Ro, CD152, GITR, LAG-3, several adhesion molecules, chemokine receptors as well as Toll-like receptors are present on the surface of Treg. Mechanism of suppression used by nTreg is not completely understood.

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Published

2016-12-29

How to Cite

1.
Frydrychowicz M, Boruczkowski M, Kolecka-Bednarczyk A, Jenek R, Rosołowska J, Pluto-Prądzyńska A, et al. Characteristics of Regulatory T cells. JMS [Internet]. 2016 Dec. 29 [cited 2024 Mar. 28];85(4):323-6. Available from: https://jms.ump.edu.pl/index.php/JMS/article/view/175

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Section

Review Papers
Received 2016-12-12
Published 2016-12-29